June 2021 in “European journal of medical and health sciences” PRP therapy is a safe and effective treatment for hair loss.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
514 citations,
February 2011 in “International journal of women's health” Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
467 citations,
May 1999 in “Molecular Cell” Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
278 citations,
May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
182 citations,
May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
164 citations,
February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
150 citations,
May 1993 in “The journal of cell biology/The Journal of cell biology” Mouse Notch is important for determining cell roles in hair follicles.
137 citations,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
136 citations,
July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
132 citations,
September 2009 in “Experimental Dermatology” A reliable system was developed to distinguish hair growth stages, aiding in identifying hair growth promoters or inhibitors.
130 citations,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
126 citations,
August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
124 citations,
November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
112 citations,
January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
99 citations,
September 2007 in “The American journal of pathology” Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
98 citations,
March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
92 citations,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
73 citations,
November 2000 in “Proceedings of the National Academy of Sciences of the United States of America” There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
72 citations,
June 2019 in “International Journal of Cosmetic Science” 18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.
68 citations,
January 2014 in “Dermatology research and practice” Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.
66 citations,
February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
65 citations,
August 2013 in “Acta Biomaterialia” The new matrix improves skin regeneration and graft performance.
61 citations,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
56 citations,
October 2016 in “Journal of dermatological science” New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
56 citations,
March 2003 in “Journal of Investigative Dermatology” 17β-estradiol can reduce inflammation in the skin.
48 citations,
April 2021 in “Journal of the American Academy of Dermatology” Topical corticosteroids are the best initial treatment for children's alopecia areata.