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150-180 / 1000+ resultsresearch Outer root sheath keratinization in anagen and catagen of the mammalian hair follicle. A seventh distinct type of keratinization in the hair follicle: trichilemmal keratinization.
This study describes trichilemmal keratinization as a distinct process of hair follicle keratinization that occurs in specific areas of the outer root sheath, illustrated using electron microscopy on dog hair.
research Microstructure of a soft tissue filling agent from hair,and experimental study of cutaneous filling
This study found that an injectable material derived from hair shows good biocompatibility and promotes dermal thickness in pigs, suggesting potential as a new soft tissue filling agent.
research A retrospective review of hyperaesthetic leucotrichia in horses in the USA
This study reports that hyperaesthetic leucotrichia primarily affects Arabian and American paint horses, occurring mainly in summer, with histological differences from erythema multiforme despite some shared features.
research EFFECTS OF HUMAN HAIR KERATIN ALKYLATION ON GROWTH FACTOR DELIVERY AND CELLULAR RESPONSE: IMPLICATIONS IN BONE REGENERATION
This research provides insights into how keratin hydrogels, modified to control disulfide crosslinking, may function as a treatment platform for bone injuries.
research Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
This review discusses the cosmetic and nutricosmetic efficacy of hyaluronic acid for skin rejuvenation and reports that HA formulations show remarkable anti-aging properties.
research VAGINAL KERATINIZATION IN VITRO*
research [A three-dimensional observation of human hair tissue treated by modified trypsin-HC1 method].
This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.
research Update on detection, morphology and fragility in pili annulati in three kindreds
This study found that careful light microscopy using fluid-mounted hair improves detection of the pili annulati phenotype, which varies widely in expression and affects hair fragility.
research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte
This study suggests that the C-terminal of AHF is crucial for its binding to keratin bundles and modulating the keratin meshwork in hair follicles.
research One‐Step Tunable Human Hair Keratin Gradient Hydrogel with Antibacterial Activity for Tissue Engineering (Small 52/2025)
This study reported that hydrogels created from keratins extracted from human hair exhibit antibacterial properties and enhance tissue regeneration, suggesting their potential use in full-thickness skin repair, as demonstrated by increased collagen production and improved healing in vivo.
research Prospective Clinical Evaluation of Cross-Linked Hyaluronic Acid Dermal Filler (30 mg) for Facial Rejuvenation
This study found that a novel cross-linked hyaluronic acid dermal filler is safe and effective for improving lip enhancement, cheekbone augmentation, and nasolabial folds across different skin types, with significant improvements in wrinkle severity and overall facial aesthetics observed.
research Skin equivalent containing collagen-human hair keratin matrice for formation of neodermis
This study found that human hair keratin can serve as a matrix for skin structure restoration, as observed in rats where the graft was replaced by newly formed collagenous fibers over six weeks.
research Cryogelation of human hair keratins
This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.
research Heparanase 1: a key participant of inner root sheath differentiation program and hair follicle homeostasis
This study found that heparanase is primarily located in the inner root sheath of human hair follicles during the anagen phase, and inhibiting it in cultured hair follicles induces a catagen-like process.
research FEMALE CADAVER IN THE HAN TOMB NO. 1 X-RAY DIFFRACTION STUDIES ON TWO KINDS OF FIBROUS PROTEIN
This study found that the molecular structures of α-keratin and collagen in a 2,100-year-old female cadaver's hair and tendon were preserved, while fibrous molecule aggregations were altered.
research Evaluation of changes in skin biophysical parameters and appearance after pneumatic injections of non-cross-linked hyaluronic acid in the face
In this study, pneumatic injections of non-cross-linked hyaluronic acid were associated with improvements in skin texture, pores, wrinkles, and transepidermal water loss in healthy female volunteers.
research Adverse cutaneous reactions to soft tissue fillers – a review of the histological features
This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
research Partial cicatricial alopecia after temporal filler with hyaluronic acid
This case study reported rare alopecia resulting from a hyaluronic acid filler injection, noting approximately 80% hair regrowth after treatment with topical minoxidil.
research A histochemical examination of the epidermis of the southern elephant seal (Mirounga leonina L.) during the telogen stage of hair growth
This study describes the structure and composition of the epidermal horny layer in elephant seals, noting that its keratinized cells are attached without a specialized fission zone, differing from the sloughing mechanism in reptiles.
research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle
research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21
research In Vitro Hair Growth Promoting Effect of a Noncrosslinked Hyaluronic Acid in Human Dermal Papilla Cells
This study found that a noncrosslinked hyaluronic acid filler restored cell viability against UVB-induced cytotoxicity and increased VEGF secretion in human dermal papilla cells, suggesting potential for mesotherapy use after further research.
research Bilateral Eyelid Pseudoptosis From Lipogranulomas of the Preaponeurotic Fat Pads
This case report concludes that the presence of distinctive histiocytic responses in a Cambodian woman's eyelid lipogranulomas suggests surreptitious silicone injections despite her denial of prior procedures.
research Ultrastructural characteristics of trichilemmal cysts: report of two cases
This study observed that the keratinization pattern of trichilemmal cysts in two Japanese women may originate from the proliferation of the outer root sheath in the follicular isthmus of anagen hairs.
research Effectiveness and Safety of a New Hyaluronic Acid Injectable for Augmentation and Correction of Chin Retrusion
This study evaluated the safety and effectiveness of HASHA, a new hyaluronic acid injectable, for chin augmentation in adults with chin retrusion. HASHA significantly improved chin appearance and satisfaction over 12 months compared to controls, with only mild or moderate transient adverse events.
research Localized syringolymphoid hyperplasia with alopecia and anhidrosis
This article describes a rare case of syringolymphoid hyperplasia with alopecia and anhidrosis in a female patient, emphasizing challenges in diagnosis and treatment unresponsiveness despite the condition's link to mycosis fungoides.
research [Electrophoretic studies of acid mucopolysaccharides in skin, prekeratin of hair follicles and in keratoses of wool].
This study found that chondroitin sulfate levels were higher than hyaluronic acid in skin and hair follicle samples, with the highest concentration observed in prekeratin of hair follicles and wool fibers.
research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
research A smart polyhydroxyalkanoate-hyaluronic acid hybrid biphasic delivery platform for enhanced Alzheimer’s symptom management via sustained huperzine A release
In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.