Bilateral Eyelid Pseudoptosis From Lipogranulomas of the Preaponeurotic Fat Pads

    September 2015 in “ Ophthalmic plastic and reconstructive surgery ”
    Frederick A. Jakobiec, Ruju Rai, Alia Rashid, Francis C. Sutula
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    Studysummary This case report concludes that the presence of distinctive histiocytic responses in a Cambodian woman's eyelid lipogranulomas suggests surreptitious silicone injections despite her denial of prior procedures.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A 49-year-old Cambodian woman developed bilateral eyelid pseudoptosis due to lipogranulomas in the preaponeurotic fat pads, likely from surreptitious silicone injections despite her denial of any prior injections. Histopathological examination revealed vesiculations surrounded by collagenous lamina and histiocytes, characteristic of silicone granulomas. Surgical excision of the abnormal fat pads restored normal eyelid function and appearance, with no recurrence over 18 months. This case underscored the importance of considering silicone injections in the differential diagnosis of similar presentations and highlighted the unique histopathologic features of lipogranulomas.
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