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Phospholipase A2 enzymes play key roles in skin health and disease.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

Different fibroblasts play key roles in skin healing and scarring.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.

PAI-2 helps in the maturation and protection of hair and nail cells.

Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Hair loss caused by genetics and hormones; more research needed for treatments.

Curcumin may help reverse aging by targeting specific genes.

Androgens can both increase body hair and cause scalp hair loss.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Hedgehog signaling in certain cells is crucial for hair growth during wound healing.

The new method can create hair follicle-like structures but not complete hair with roots and shafts, needing more improvement.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Skin organoids from stem cells can help study and treat skin issues but face some challenges.