41 citations,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
45 citations,
April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
116 citations,
April 1986 in “The journal of cell biology/The Journal of cell biology” Trichohyalin is a protein in hair follicles that helps form hair filaments.
13 citations,
March 2021 in “British Journal of Pharmacology” KY19382 helps regrow hair and create new hair follicles.
2 citations,
June 2001 in “American Journal of Pathology” The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
17 citations,
April 2021 in “Molecules/Molecules online/Molecules annual” Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
13 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.
1 citations,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
209 citations,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
11 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” New cell-based therapies may improve hair loss treatments in the future.
159 citations,
October 2015 in “Science Advances” Blocking JAK-STAT signaling can lead to hair growth.
136 citations,
July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
16 citations,
January 2018 in “International Journal of Trichology” Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
13 citations,
April 2010 in “Journal of dermatological science” Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.
10 citations,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
114 citations,
October 1996 in “Dermatologic clinics” Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
83 citations,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
July 2019 in “Journal of Investigative Dermatology” The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.
51 citations,
April 2020 in “Cells” Special cell particles from macrophages can help hair grow.
June 2012 in “Nature digest” A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.
98 citations,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
39 citations,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
18 citations,
December 2020 in “Frontiers in cell and developmental biology” miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.
14 citations,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
March 2024 in “Journal of Microbiology and Biotechnology” Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.