Histochemistry of the Human Hair Follicle with Consideration of Anagen Phases I to VI

The study investigated the histochemistry of human hair follicles, focusing on the anagen phases I to VI. It found that proliferative peripheral cells, identified using the Ki67 antibody, were distributed throughout the intraglandular and intradermal ducts, unlike other epidermal appendages where proliferation was limited to the base. This distribution pattern was unique, as cells in the intradermal duct began differentiating while moving upward alongside proliferative cells. The study also noted the focal expression of K1 and K10 in these peripheral cells, highlighting a distinct differentiation process within the sweat duct compared to other epithelial layers of the hair follicle.