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The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Researchers identified specific genes that are important for mouse skin cell development and healing.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Honokiol helps protect skin from damage and aging caused by cigarette smoke.

Green tea may help with skin health and protect against UV damage, but more research is needed to confirm its safety and effectiveness.

Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

New treatments for hair loss may target specific pathways and generate new hair follicles.

Korean Red Ginseng may protect against hair loss caused by chemotherapy.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Some chemicals absorbed through the skin can cause serious health problems.

Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Higher androgen levels do not cause baldness in men.

Certain gene mutations are linked to wool quality in sheep and could help in breeding for better wool.

Compounds from the plant Mammea siamensis may help treat hair loss.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

Hair in mammals likely evolved from glandular structures, not scales.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Type 2 diabetes may increase the risk of severe hair loss in African American women.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Substances from dental stem cells might help treat hair loss.