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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Low-level laser therapy helps hair growth and reduces hair loss with few side effects.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

PRP treatment helps hair growth in most cases, but more research needed.

The method accurately measures testosterone metabolites with high sensitivity and low environmental impact.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

The study created a new method to test drugs that affect hormone processing in skin.

The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.

Stem cell therapy affects 15 key genes in rats with diabetes-related erectile dysfunction.

Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.

Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.

There is a significant relationship between androgenic alopecia, hypertension, and diabetes mellitus.

A man got heart and swelling issues from a hair loss medication, so doctors advise careful use, especially in people with past health problems.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.

Stopping minoxidil and draining fluid around the heart can save lives in rare cases.

Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.