Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that estrogen receptor beta, not alpha, is the main mediator of estrogen action in human skin and hair follicles, suggesting a distinct role in these tissues.

This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.

This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.

In this study, researchers identified novel LMNA mutations in patients with atypical progeroid syndrome, revealing clinical features distinct from other similar disorders, but unrelated to mutant prelamin A accumulation.

In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.

This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.

This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.

This overview discusses primary cicatricial alopecias, focusing on lichen planopilaris, and highlights the challenges in treatment and the progressive nature of hair loss despite symptom management, without providing new clinical results.

This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.

This review describes the roles of 5α-reductase isozymes in prostate development and pathology and reports no new clinical results.

This study found that the retinoid all-trans retinoic acid induced a catagen-like stage in human scalp hair follicles, suggesting upregulation of TGF-beta2 as a contributing mechanism.

This review discusses how circadian clocks may influence diverse physiological functions beyond their established role in daily timekeeping, but it reports no new experimental findings.

This study found that red ginseng oil may enhance hair growth and protect skin from UV damage in mouse models by promoting regenerative processes and reducing inflammation.

This review discusses the genetic factors involved in hair follicle morphogenesis and cycling and reports no new clinical results; it emphasizes the role of genes in hereditary hair diseases.

This study shows that BMP2 and BMP7 play complex, necessary roles in feather development by regulating dermal condensation formation, with BMP7 acting early as a chemoattractant and BMP2 halting cell migration.

This review discusses recent insights into the molecular mechanisms of hypohidrotic ectodermal dysplasia linked to TNFα-related signaling pathway mutations but reports no new experimental results.

This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.

This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.

This study found that the absence of the vitamin D receptor disrupts hair follicle structure during the first catagen in mice, linked to increased expression of the hairless gene.

This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.

This review discusses recent advances and ongoing clinical trials in novel therapeutics for alopecia areata, despite the lack of current FDA-approved treatments for severe cases, and reports no new results.

This review discusses circadian clock regulation in stem cells and its role in processes like neurogenesis, but reports no new results; the authors emphasize its significance in stem cell function across various tissues.

In this study, specific genetic polymorphisms in the KRT71 gene were associated with hairless and curly phenotypes in Sphynx and Devon Rex cats.

This review examines the role of Hairless, a nuclear receptor corepressor, in regulating Wnt signaling during hair cycling and reports no new clinical results.

This study suggests that S100A4 and S100A6 proteins may play key roles in activating stem cells for hair follicle regeneration in mice.

This review discusses the JAK-STAT pathway and the use of FDA-approved JAK inhibitors for autoimmune and inflammatory diseases but reports no new research findings.

This article reviews the coordination of the hypothalamic-pituitary-gonadal axis, male fertility, and therapies for hypogonadism, but reports no new clinical findings.

This review summarizes existing knowledge on the role of FOXN1 as a key regulator of thymic epithelial cell lineage and function, reporting no new experimental results.