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Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Oestrogens are key for bone growth during puberty in both boys and girls.