research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
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research Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Identification and Characterization of an Antisense RNA Transcript (GFG) from the Human Basic Fibroblast Growth Factor Gene
Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
research Hair Weathering: Degeneration of Hair by Environmental and Cosmetic Factors
Avoid chemical and physical damage to protect hair.
research Formulation and Evaluation of Halal Hair Growth Promoting Shampoo Containing Centella Asiatica and Phyllanthus Emblica
The shampoo effectively promotes hair growth and is halal-compliant.
research Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells
Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
research Lupus Panniculitis Clinically Simulating Alopecia Areata
Lupus can look like hair loss from alopecia areata but needs different treatment.
research Glucose and Acetate Metabolism by Isolated Sheep Wool Follicles
Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.
research Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Announcements
A woman with lupus had hair loss and skin issues that were successfully treated with medications.
research Association Analysis of Polymorphisms in Six Keratin Genes with Wool Traits in Sheep
Certain gene mutations are linked to wool quality in sheep and could help in breeding for better wool.
research Self-Emulsifying Drug Delivery Systems (SEDDS): Measuring Energy Dynamics to Determine Thermodynamic and Kinetic Stability
Solidified SEDDS improve drug stability and bioavailability better than liquid SEDDS.
research Metal Chelation Assisted Deposition of Polydopamine on Human Hair: A Ready-to-Use Eumelanin-Based Hair Dyeing Methodology
Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
research Development of Finasteride Polymer Microspheres for Systemic Application in Androgenic Alopecia
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
research A Quantitative Assessment of Wound Healing With Oxygenated Micro/Nanobubbles in a Preclinical Burn Model
Oxygenated micro/nanobubbles speed up burn wound healing in rats.
research Hair Masks Based on Keratin and Collagen
The hair masks are safe, stable, and effective for hair care.
research Promotion Effect of Constituents from the Root of Polygonum Multiflorum on Hair Growth
Compounds from Polygonum multiflorum root, especially a new one, can boost hair growth more effectively than common treatments.
research Pharmacological BACE1 and BACE2 Inhibition Induces Hair Depigmentation by Inhibiting PMEL17 Processing in Mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research Liposomes with an Ethanol Fraction as an Application for Drug Delivery
Ethosomes improve drug delivery through the skin but may have side effects like irritation.
research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal
Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
research Effect of Disulfide Bonds in Human Hair Fibers on the Melting Behavior of Their Crystalline Structure
Changing disulfide bonds in human hair affects its melting behavior and thermal stability.
research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant
A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
research BMP4 Regulates Differentiation of Nestin-Positive Stem Cells Into Melanocytes
BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
research A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride
Desolvation of finasteride depends on environment and technique.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Potential Remedial Effects of Solanum Nigrum Berries on Alopecia: An In Vivo Study
Solanum nigrum extract may help regrow hair.
research The Influence of Menthol in Ethanol Extract of Phyllanthus Niruri Gel as a Hair Growth Promoter in Male Wistar Rats
Menthol boosts the hair growth effects of Phyllanthus niruri gel.