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Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

New effective scar treatments are urgently needed due to the current options' limited success.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Skin fat helps with body temperature control and has other active roles in health.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mutant mice help researchers understand hair growth and related genetic factors.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Fat tissue stem cells may help increase hair growth.

Muscles and nerves that cause goosebumps also help control hair growth.

Certain mice without specific receptors or mast cells don't lose hair from stress.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.