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Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Skin problems are very common in people with end-stage kidney disease.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.