November 2024 in “Journal of Investigative Dermatology” This study identified PTEN as a key regulator in non-healing venous leg ulcers, suppressing immune responses and lymphangiogenesis, suggesting its potential as a therapeutic target for promoting VLU healing.
37 citations
,
November 2020 in “International Journal of Nanomedicine” Nano-liposol with astaxanthin may improve antioxidant and wound healing effects.
4 citations
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May 2023 in “Composites Part B: Engineering” In this study, a novel nanocomposite hydrogel was developed for diabetic wound care, demonstrating superior tissue adhesion, antibacterial properties, and healing capabilities in vivo and in vitro, while also allowing real-time pH monitoring to aid clinical management.
4 citations
,
January 1987 in “Journal of The American Academy of Dermatology” A man with both skin lesions and lung cancer improved quickly with chemotherapy, suggesting the skin condition might be a reaction to immune system injury.
150 citations
,
June 2014 in “Biomaterials” This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.
2 citations
,
October 2020 in “Drug Discoveries & Therapeutics” This study observed that Althaea officinalis gel increased fibroblast populations, hair follicles, and vessel diameter in rat wounds, suggesting it might aid wound healing, though further clinical studies are needed.
This study suggests that human hair keratin-based gradient hydrogels incorporating silver ions may serve as promising dermal templates for wound healing, demonstrating favorable mechanical properties, cell interaction, and antibacterial activity.
14 citations
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March 2025 in “Nano Today” The hydrogel dressing speeds up and improves diabetic wound healing.
8 citations
,
July 2023 in “Inflammation and Regeneration” This study found that ALKBH5 plays a critical role in wound re-epithelialization by enhancing the stability of PELI2 mRNA, and its absence delays wound healing. Supplementation with PELI2 can partially rescue this delay, pointing to potential new therapies for stubborn wounds.
8 citations
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October 2022 in “International Journal of Molecular Sciences” This study found that CLD-hFGF2 hydrogels improved healing in deep second-degree burn wounds more effectively than hydrogels alone or direct administration of CLD-hFGF2.
This study developed a directional pressure-pump hydrogel delivery platform that enhances wound healing in diabetic mechanically dynamic wounds by targeting antibacterial agents and nanozymes directly to the lesion site, disrupting biofilms, mitigating tissue damage, and supporting proper skin closure and vascular remodeling in animal models.
February 2024 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that human platelet lysate, prepared from expired platelet concentrate, maintained stable growth factor levels for up to six months and improved healing in second-degree burn wounds compared to standard silver sulfadiazine treatment at three weeks.
34 citations
,
August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
Low level laser or LED therapy combined with infiltrations may help hair growth.
10 citations
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January 2025 in “Biomaterials Science” This study found that a multifunctional hydrogel dressing enriched with Cu-MOF and tannic acid significantly improved full-thickness wound healing in rats, reducing the wound area to only 1.6% and promoting re-epithelialization, neovascularization, and hair follicle formation.
25 citations
,
January 2018 in “Acta Clinica Croatica” This study found that allogeneic platelet gel significantly improved healing in non-healing chronic lower leg ulcers compared to hydrogel treatment.
13 citations
,
January 1996 in “PubMed” This study suggests that silver-coating may enhance the healing of exit sites in peritoneal catheters in rats, with similar tunnel histomorphology indicating favorable biocompatibility compared to standard catheters.
December 2025 in “Jurnal Ilmiah Kesehatan (JIKA)” This study found that a 15% concentration of Wilalondahi bark extract gel significantly improved wound healing and reduced inflammation in mice, with wounds completely healed by day 9, demonstrating comparable effectiveness to the positive control.
37 citations
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December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
February 2026 in “Nano Research” In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.
6 citations
,
December 2024 in “International Journal of Biological Macromolecules” This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.
November 2024 in “Journal of Investigative Dermatology” Serotonin helps wounds heal faster.
12 citations
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September 2023 in “Polymers” This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.
10 citations
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August 2024 in “Chemical Engineering Journal” This study found that a microenvironment-responsive ATAN-Met hydrogel system improved infective diabetic wound healing by enhancing re-epithelialization, neurovascular and hair follicle regeneration, and exhibited antibacterial and immunoregulatory effects, activated beneficial pathways, and responded to glucose/ROS for drug release.
April 2025 in “International Journal of Homoeopathic Sciences” In this case study, individualized classical homeopathy was reported to effectively promote significant hair regrowth and improve emotional stability in a patient with alopecia areata, showcasing a potential holistic and sustainable alternative to conventional treatments.
5 citations
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June 2015 in “The Journal of Dermatology” This study identified "HTLV-1-associated lichenoid dermatitis" as a skin condition in HTLV-1-infected individuals, characterized by reactive eruptions associated with increased immunity toward infected CD4+ T cells.
1 citations
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August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study presents a composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers that demonstrates effective antibacterial properties, enhanced mechanical strength, and promotes wound healing.
10 citations
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July 2023 in “Pharmaceuticals” This study explored the wound healing potential of a natural marine soft coral-derived nanoparticle-based gel in a diabetic excision wound model, finding it effectively regulates proinflammatory cytokines and inhibits enzymes related to wound healing.
August 2025 in “Acta Biomaterialia” This study presents a novel hydrogel scaffold made from tilapia collagen, which when activated by ultrasound, reprograms macrophages to promote wound healing, enhance angiogenesis, and stimulate hair follicle regeneration, offering a potential new method for treating inflammatory wounds.
December 2025 in “Regenerative Biomaterials” In this study, researchers developed a responsive bilayer hydrogel for diabetic wounds that delivers drugs and oxygen in sync with healing stages, achieving a 99.1% wound closure rate in 14 days by integrating anti-inflammatory, antibacterial, and anti-fouling functions.