1 citations
,
November 2024 in “Journal of Investigative Dermatology” Er:YAG laser therapy effectively treats Hailey-Hailey disease, leading to long-term remission and improved quality of life.
25 citations
,
June 2018 in “Journal of The American Academy of Dermatology” This study identified upregulation of genes linked to fibroproliferative disorders, such as platelet-derived growth factor and collagen genes, in patients with central centrifugal cicatricial alopecia, suggesting potential therapeutic targets.
1 citations
,
December 2023 in “JAAD International” Mast cells may significantly contribute to central centrifugal cicatricial alopecia.
90 citations
,
July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
January 2022 in “Mammalian Genome” This study found that the wavy coat trait in Nakano cataract mice is polygenic, involving major and minor genes, and resembles human curly scalp hair associated with the PRSS53 gene alteration.
March 2025 in “Journal of Drugs in Dermatology” This study developed a physician-guided algorithm to manage cutaneous adverse events from hormonal therapy in cancer patients, aiming to reduce treatment interruptions and enhance quality of life.
1 citations
,
April 2015 in “Iranian Journal of Clinical Infectious Diseases” This study found no significant difference in H. pylori antibody levels between women with and without PCOS, suggesting H. pylori infection may not influence infertility in these women.
January 2015 in “Springer eBooks” This chapter reviews polycystic ovary syndrome's clinical features, highlighting diagnostic criteria and management strategies, and reports no new findings; the authors emphasize the need for targeted treatment approaches.
10 citations
,
June 2019 in “Dermatologic therapy” In this study, treatment with DPCP alone was more effective for hair regrowth and presented fewer side effects in chronic extensive alopecia areata compared to combination therapy with DPCP and anthralin.
August 2010 in “Journal of Investigative Dermatology” New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.
January 2026 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” In this study, cicatricial alopecias were classified by inflammatory cell type and the researchers highlighted that primary cicatricial alopecia's exact causes remain unknown, accounting for 6% of all hair diseases despite its unclear prevalence.
January 2002 in “Agritrop (Cirad)” This study found that mutations in exon 3 of the hr gene are strongly associated with congenital hypotrichosis in Valle del Belice sheep, suggesting a potential genetic link to the disorder.
May 2023 in “Research Square (Research Square)” This study investigated the effects of HDDPiW-jSB solution on chemotherapy-induced alopecia in a rat model and found that the solution improved hair follicle health markers and reduced cell apoptosis, especially when applied twice weekly, while appearing safe for skin application.
July 2025 in “Journal of Investigative Dermatology” Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.
January 2024 in “Oxford medical case reports” This case report details the first observed instance of congenital erythropoietic porphyria in Armenia, where standard treatments did not stop symptom progression in a 22-year-old man, prompting consideration of stem cell transplant.
This study found that a hair growth rate of 0.75 cm/month better matches retrospective cortisol timelines and identified factors influencing hair cortisol content in children and adolescents.
August 2025 in “Frontiers in Immunology” This study found that patients with primary cicatricial alopecia are at higher risk of developing various comorbidities, including systemic lupus erythematosus, hypothyroidism, and dermatological conditions, compared to controls.
41 citations
,
May 2020 in “Frontiers in immunology” This review discusses the genetic, autoinflammatory, and keratinization factors involved in hidradenitis suppurativa and presents the concept of classifying it as an autoinflammatory keratinization disease, but reports no new clinical results.
42 citations
,
December 1976 in “PubMed” This study found that the combination of cyproterone acetate and ethinyl estradiol improved hirsutism and acne in women, with SH 8.1041 showing significant results and both treatments being generally well-tolerated.
2 citations
,
November 1998 in “Journal of The European Academy of Dermatology and Venereology” This article reports on a partial regrowth of scalp hair in a patient treated with extracorporeal photochemotherapy and interferon α 2a, but provides no new clinical outcomes.
January 2016 in “Methods in molecular biology” This study identified a population of GFP-expressing nestin-positive cells in transgenic mice hair follicles that varied in location during different hair cycle phases, suggesting a shared relationship with neural stem cells.
April 2008 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the diagnosis and management of hirsutism in women, discussing its causes, assessment, and treatment options; no new clinical findings are included.
12 citations
,
April 2016 in “PLoS ONE” This study found that the Chinese version of the Polycystic Ovary Syndrome Quality of Life Questionnaire (Chi-PCOSQ) is sensitive to clinical changes and effectively assesses health-related quality of life in Chinese women with PCOS.
6 citations
,
July 2017 in “Biochemical and Biophysical Research Communications” This study found that mutations in the hairless gene disrupt normal hair follicle development by impairing Wnt/β-catenin signaling, affecting hair keratinocyte differentiation in both mice and humans.
27 citations
,
December 2005 in “Journal of Cutaneous Pathology” This study found that while malignant pilomatricomas maintain some keratin expression patterns seen in benign counterparts, they notably express additional epithelial keratins, potentially influencing tumor calcification.
31 citations
,
August 2019 in “Regenerative Medicine” This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.
10 citations
,
December 2015 in “International Journal of Molecular Sciences” This study suggests that PDCD4 regulates keratinocyte proliferation and contact inhibition, playing a role in epidermal homeostasis and wound healing.
5 citations
,
November 2023 in “Journal of Investigative Dermatology” People with primary cicatricial alopecia have a higher risk of heart disease and stroke.
1 citations
,
December 2011 in “Arzneimittelforschung” This study developed a sensitive HPLC-MS/MS method for determining cyproterone acetate levels in human plasma and found no significant difference in its concentration between two oral formulations in bioequivalence testing.
4 citations
,
October 2020 in “Therapeutic drug monitoring” In this study, researchers found that targeting a tacrolimus trough level of 4–7 ng/mL after liver transplantation resulted in comparable graft and patient survival rates to higher levels, while improving liver and kidney function markers.