The Efficacy of HDDPiW-jSB Solution on Docetaxel-Induced Alopecia in Rats

    Bilgin Demir, Buket Demirci, Canten Tataroğlu … Duygu Barutca

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study investigated the effects of HDDPiW-jSB solution on chemotherapy-induced alopecia in a rat model and found that the solution improved hair follicle health markers and reduced cell apoptosis, especially when applied twice weekly, while appearing safe for skin application.
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    Research cited in this study 8

    1. The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function EMBO Reports · 2021
    2. Cancer Treatments and Alopecia: A Systematic Review Turkiye Klinikleri Journal of Internal Medicine · 2021
    3. The Role of Vitamins and Minerals in Hair Loss: A Review Dermatology and Therapy · 2018
    4. Permanent Chemotherapy-Induced Alopecia in Patients with Breast Cancer: A 3-Year Prospective Cohort Study ˜The œoncologist · 2018
    5. Evaluation of Animal Models Suitable for Hair Research and Regeneration InTech eBooks · 2018
    6. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    7. Presentation, Impact and Prevention of Chemotherapy-Induced Hair Loss: Scalp Cooling Potentials and Limitations Expert review of dermatology · 2011
    8. Taxane-Induced Alopecia: A Historical Review of Patients With Ovarian or Breast Cancer Treated With Paclitaxel, Docetaxel, or Paclitaxel Poliglumex Journal of Clinical Oncology · 2005

    Related research 4

    1. Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions Toward Clinical Reality ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2016
    2. Parathyroid Hormone Linked to a Collagen Binding Domain Promotes Hair Growth in a Mouse Model of Chemotherapy-Induced Alopecia in a Dose-Dependent Manner Anti-Cancer Drugs · 2014
    3. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    4. Expanding Research and Development of Novel Agents for the Treatment and Prevention of Chemotherapy-Induced Alopecia Expert Opinion on Therapeutic Patents · 2006