Individual Article: USCOM V: A Practical Algorithm for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy

March 2025 in “ Journal of Drugs in Dermatology ”

Jennifer Choi, Mario E. Lacouture, Anneke Andriessen, Alice Y. Ho, Beth N. McLellan, Edith Mitchell, Jonathan S. Leventhal

androgenic alopecia hirsutism xerosis pruritus brittle nails hormonal cancer therapy CTCAE v.5 skin disorders hair loss dry skin itching hormone therapy Common Terminology Criteria for Adverse Events

TLDR A new method helps manage skin side effects from hormonal cancer therapy, improving patient care.

The article presents a physician-developed algorithm designed to prevent and manage cutaneous side effects associated with hormonal cancer therapy, which is crucial for patients with hormone-dependent cancers like breast and prostate cancer. These side effects include signs of aging, xerosis, pruritus, brittle nails, androgenic alopecia, and hirsutism. The algorithm, developed through a systematic literature review and expert panel input, uses the CTCAE v.5 grading system for skin disorders related to cancer therapy. By implementing this algorithm, clinicians can potentially reduce treatment interruptions, enhance patient outcomes, and improve the quality of life for patients undergoing hormonal cancer therapy.

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Individual Article: USCOM V: A Practical Algorithm for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy

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