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Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

TTD hair brittleness is caused by multiple structural abnormalities.

Isolated patchy heterochromia with pili annulati can occur without other health issues.

Fractionated laser therapy, especially erbium-glass laser, effectively increases hair thickness in people with hair loss but doesn't increase the number of hairs.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Monilethrix causes fragile, patchy hair loss.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Three dogs with a rare skin condition improved with treatment.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.

Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.

Persistent radiation-induced hair loss is dose-dependent, and treatments like topical minoxidil can be effective.

Mouse models help understand alopecia areata and find treatments.

Different body areas in mice produce different hair types due to interactions between skin layers.

Different processes create patterns in skin and things like hair and feathers.

The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.

Fat-related cells are important for initiating hair growth.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.