Dermatopathia Pigmentosa Reticularis: A Rare Reticulate Pigmentary Disorder

Dermatopathia pigmentosa reticularis (DPR) is a rare ectodermal dysplasia characterized by generalized reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy. This case report described a 21-year-old woman with these symptoms, along with palmoplantar keratoderma and poorly developed dermatoglyphics. Histopathology showed basal layer degeneration and absence of skin adenexa. DPR is inherited in an autosomal dominant fashion and persists throughout life without specific treatment, though symptomatic management for conditions like hyperkeratosis can be beneficial. The disorder is related to mutations in the keratin 14 gene.