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This study found that the patch assay effectively reconstituted mature hair follicles using culture-expanded human fetal cells and may serve as a method to assess cell trichogenicity.

This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.

In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.

In this study, researchers developed a drug-free microneedle patch using chitosan lactate and stem cell-derived exosomes that significantly promotes hair regeneration in animal tests compared to minoxidil, highlighting its potential as a simple and efficient hair loss treatment.

This study found that a green-light LED microneedle patch enhanced hair growth in mice with the best results among tested wavelengths, showing increased hair follicles and no serious side effects, suggesting its potential for treating androgenetic alopecia.

This study found that a bioorthogonal microneedle patch delivering AAV-aFGF effectively improved hair follicle regeneration and sustained hair growth in murine alopecia models compared to other methods.

This study developed a bifunctional sodium hyaluronate microneedle patch incorporating glycyrrhizin-loaded dutasteride micelles and mesoporous polydopamine nanoparticles, which effectively inhibited DHT and reduced ROS in hair follicle cells, resulting in significantly accelerated hair growth in vitro and in vivo.

This study found that a microneedle patch with recombinant collagen XVII significantly improved hair coverage, follicle density, and angiogenesis in an androgenic alopecia mouse model, showing potential as a novel therapeutic strategy alongside established treatments like minoxidil.

This study reported that a curcumin-zinc microneedle patch improved hair regrowth and wound healing in animal models, suggesting potential as a versatile treatment for hair loss.

In this study, a patch with microneedles regrew hair in shaved mice within six days, suggesting potential for treating hair loss in humans.

Focus on general hair care and lifestyle changes.

This study reports that a water-soluble microneedle patch with minoxidil-loaded microspheres showed similar or better hair regeneration effects in mice with less frequent application compared to daily topical minoxidil.

This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.

This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.

This review discusses the need for an updated 'European hair cosmetic series' to include common contact allergens and remove outdated substances based on current evidence and regulations, but it reports no new results.

This case report details a 17-year-old female with anorexia nervosa who presented with a large, irregular area of pubic hair loss exhibiting various hair and skin abnormalities.

This case report discusses a young girl with loose anagen hair syndrome, highlighting the importance of recognizing the condition early to avoid misdiagnosis and unnecessary treatments, and noting her spontaneous improvement with conservative management.

This study identified a specific genetic variant in the CCHCR1 gene that may contribute to alopecia areata through impaired keratinization, suggesting an alternative mechanism beyond autoimmune causes.

This study found that the majority of "hypoallergenic" hair dyes still triggered allergic reactions in patients sensitive to para-phenylenediamine.

In this study, hair tonic containing 15% patchouli leaf extract showed the greatest hair growth in rabbits, with higher concentrations leading to faster regrowth.

This study found that the patchwork mutation in mice affects melanocyte survival in hair follicles, leading to a variegated coat pattern without partially pigmented hairs due to a community effect among melanoblasts.

This study demonstrated that a new technology combining microneedle patches, stem cell exosomes, and light therapy effectively promoted hair regrowth in animal models within 7 days compared to conventional treatments.

This study reported that Sonic hedgehog signaling is crucial for hair follicle development, with its expression being significantly induced in normal embryonic hair germs but inhibited in certain experimental models.

This study found that a hair tonic formulation containing 1.5% light fraction patchouli oil demonstrated strong antifungal activity against Malassezia globosa and promoted hair growth in rabbits, suggesting potential benefits for hair care despite the need for human clinical trials to confirm safety and effectiveness.

This study found that the severity of acute donor site effluvium after hair transplants was significantly correlated with the number of grafts extracted and longer surgery durations.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

In this case report, a 7-year-old boy with patchy hair loss due to alopecia areata showed significant hair regrowth and improvement in psychological well-being after a holistic homeopathic treatment identified emotional distress as a root cause.

In this case report, a 53-year-old woman with Little-Graham-Piccardi-Lassueur-Syndrome responded well to a treatment regimen of hydroxychloroquine, methotrexate, and other therapies, effectively halting the progression of this rare dermatosis characterized by alopecia and hyperkeratotic eruptions.

This abstract presents a patient case study and does not report new research findings.

Results are not reported in this abstract, which describes a man in his 30s with a 4-year history of patchy hair loss on the right lower leg and associated itching, highlighting the use of dermoscopy in his examination.