Hybrid Function Of Light Fraction Patchouli Oil In Hair Care Formulations For Effective Hair And Anti-Dandruff Treatment
April 2025
in “
Narra J
”
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Studysummary This study found that a hair tonic formulation containing 1.5% light fraction patchouli oil demonstrated strong antifungal activity against Malassezia globosa and promoted hair growth in rabbits, suggesting potential benefits for hair care despite the need for human clinical trials to confirm safety and effectiveness. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigates the use of light fraction patchouli oil (LFPO) in hair care formulations to address hair loss and dandruff caused by Malassezia globosa. Three concentrations of LFPO (0.5%, 1.0%, and 1.5%) were tested for stability, pH, viscosity, and antifungal activity. The 1.5% LFPO formulation showed the strongest antifungal activity, with a 31.18 mm inhibition zone against M. globosa, outperforming ketoconazole. In rabbits, this formulation reduced epidermal cell shedding, increased hair length by 41.6 mm after six weeks, and promoted dense hair follicle growth. While results are promising, human trials are needed to evaluate efficacy and safety.
