Hybrid Function Of Light Fraction Patchouli Oil In Hair Care Formulations For Effective Hair And Anti-Dandruff Treatment

    April 2025 in “ Narra J ”
    Nadia Isnaini, Syaifullah Muhammad, Vicky Prajaputra, Indra Indra, Elly Sufriadi, Ernawati Ernawati, C D Riski
    TLDR Light fraction patchouli oil at 1.5% effectively treats dandruff and promotes hair growth.
    The study investigates the use of light fraction patchouli oil (LFPO) in hair care formulations to address hair loss and dandruff caused by Malassezia globosa. Three concentrations of LFPO (0.5%, 1.0%, and 1.5%) were tested for stability, pH, viscosity, and antifungal activity. The 1.5% LFPO formulation showed the strongest antifungal activity, with a 31.18 mm inhibition zone against M. globosa, outperforming ketoconazole. In rabbits, this formulation reduced epidermal cell shedding, increased hair length by 41.6 mm after six weeks, and promoted dense hair follicle growth. While results are promising, human trials are needed to evaluate efficacy and safety.
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