36 citations,
March 2011 in “Nature Communications” Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
February 2023 in “Scientific Reports” Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.
15 citations,
August 2017 in “International Journal of Molecular Medicine” Panax ginseng extract may help prevent hair loss caused by DKK-1.
3 citations,
March 2016 in “Journal of Cosmetic Dermatology” GPIGS peptide increases thick hair growth in balding Japanese men.
39 citations,
December 2013 in “Phytotherapy Research” Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
19 citations,
May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.
3 citations,
July 2015 in “European Journal of Dermatology” AGEs may cause hair loss by increasing inflammation in hair follicles.
65 citations,
September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
7 citations,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
December 2018 in “Journal of Medicinal and Aromatic Plant Sciences” Some plants like Eclipta alba, Nardostachys jatamansi, and Rumex japonicus may help hair growth.
5 citations,
October 1988 in “Clinics in Dermatology” Minoxidil promotes hair growth but exact mechanism is unknown.
June 2022 in “Pflügers Archiv - European Journal of Physiology” The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.
8 citations,
June 2012 in “PloS one” Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
3 citations,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ILC1 cells contribute to hair loss in alopecia areata.
April 2024 in “Biomedicine & pharmacotherapy” Pilose antler extract helps hair grow in mice with a type of hair loss by speeding up the growth phase.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
162 citations,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
38 citations,
September 2011 in “PLOS ONE” Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.
28 citations,
October 2004 in “Differentiation” A gene deletion causes the "hairless" trait in Iffa Credo rats.
338 citations,
April 2001 in “Current Biology” c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
43 citations,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
16 citations,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
207 citations,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
30 citations,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
3 citations,
November 2018 in “Curēus” The cause and importance of misplaced oil glands in the hair follicle are not well understood.
January 2023 in “Open Life Sciences” VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.