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Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Cannabinoids may help treat various skin conditions.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Macrophage iron release is crucial for hair growth and wound healing.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

VDR regulation varies by tissue and is crucial for its biological functions.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

NIPP1 is important for healthy skin and could help treat skin inflammation.

SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

Different light affects cell functions and can help treat skin conditions.

Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.

New near-infrared OLED emitters are more efficient, especially platinum(II) complexes, and have promising applications like hair growth treatment.

The new adhesive nanoparticles are effective for delivering Minoxidil to the scalp without skin irritation.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.

Proper incision techniques can make face-lift scars less noticeable.

A new HRAS gene variant may cause a range of symptoms including intellectual disability and psychiatric issues.

No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.