4 citations
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January 2018 in “Forensic Science International” This study reported that a newly developed UHPLC-MS/MS method detected illegal synthetic hair-growth compounds in 10% of 76 hair-growth products, highlighting the need for ongoing monitoring to protect public health.
2 citations
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June 2022 in “Cells” The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.
2 citations
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November 2017 in “Food Additives & Contaminants: Part A” This study developed a validated method to detect prohibited drugs in dietary supplements, finding minoxidil, triaminodil, and finasteride in some samples.
February 2026 in “Chromatographia” This study used advanced chromatographic and mass spectrometric techniques to develop a method for reliably detecting 17 hair growth compounds in consumer products, aiming to enhance regulatory compliance and ensure consumer safety against illicit compounds.
January 2018 in “Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment” This study developed and validated a method using UPLC-PDA and LC-Q-TOF/MS to identify and measure prohibited substances in dietary supplements, showing reliable detection of compounds like minoxidil and finasteride.
8 citations
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July 2017 in “Biochemical and biophysical research communications” This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.
5 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.
January 2019 in “Analytical Science and Technology” This study developed a rapid method using advanced chromatography and mass spectrometry to detect hair-growth enhancing compounds, discovering synthetic drugs in about 21% of tested supplements.
17 citations
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May 2018 in “PeerJ” This study found that VB-1, a vitexin compound, may promote hair follicle growth by enhancing Wnt/β-catenin signaling in human dermal papilla cells in vitro.
14 citations
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July 2021 in “Biomolecules” This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.
7 citations
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January 2017 in “Biological & Pharmaceutical Bulletin” This study found that polyacetylene compounds in Panax ginseng extracts may inhibit neurotrophin receptor binding, suggesting potential therapeutic benefits for alopecia and other hair growth disorders.
January 2025 in “International Journal of Advanced Research in Science Communication and Technology” This systematic review highlights the potential of herbal shampoos, formulated with ingredients like Neem, Bhringraj, and Aloe Vera, to promote hair growth and reduce dandruff, while also discussing modern techniques and challenges in their development and evaluation.
This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.
This study found that VB-1, a vitexin compound, may promote human hair follicle growth by enhancing Wnt/β-catenin signaling in dermal papilla cells.
October 2017 in “Institutional Repositories DataBase (IRDB)” Polyacetylene compounds from Panax ginseng may slow hair growth.
June 2018 in “JoLS Journal of Life Sciences” The fermented mixture may help hair growth and has antioxidative benefits.
This study found that the lignan compound VB-1 may promote hair follicle growth by enhancing Wnt/β-catenin signaling and increasing dermal papilla cell proliferation in vitro.
In this in vitro study, Yifa Compound Prescription was reported to enhance human hair follicle growth and increase VEGF mRNA expression compared to blank serum.
July 2022 in “Institutional Repositories DataBase (IRDB)” 3D spheroid cells effectively test hair growth compounds like Minoxidil.
19 citations
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October 1988 in “Clinics in dermatology” This article discusses potential roles for retinoids in hair regrowth and proposes future studies, reporting no new experimental results.
This study found that the methanolic heartwood extract of Avicennia marina significantly inhibited the enzyme 5 alpha-reductase type 1 in a cell-based assay, suggesting potential anti-androgenic effects for treating androgenic alopecia.
January 2020 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study concluded that TrichoxidilTM positively affected hair growth by increasing growth factor expression and fibroblast proliferation, suggesting it may be a promising treatment for androgenetic alopecia.
July 2025 in “Dermatologica Sinica” In this study, compound glycyrrhizin promoted hair regrowth in a testosterone-induced alopecia mouse model and increased human hair dermal papilla cell proliferation, likely through activating the Wnt/β-catenin pathway.
6 citations
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November 2019 in “Journal of Cosmetic Dermatology” This study found that applying a 1% BOI lotion improved hair density and thickness in patients with mild pattern hair loss over six months.
November 2021 in “Research Square (Research Square)” This study found that human hair follicle dermal papilla cells grown in a 3D model influenced hair growth and immune pathways more effectively than those grown in a 2D culture.
5 citations
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May 2022 in “Biomedicines” This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.
November 2022 in “Bioengineering” This study developed immortalized cell-based models to screen and evaluate potential hair-care materials by forming hair follicle-like structures that respond to hair growth-promoting compounds.
15 citations
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April 2001 in “Journal of Dermatological Science” This study found that KF19418 stimulated hair follicle growth in vitro and accelerated hair regrowth in a mouse alopecia model, with effects comparable to minoxidil.
This study found that a modified scaffold with VEGF165 genetically modified hair follicle stem cells significantly promoted blood vessel growth and wound healing in rats, suggesting its potential as a skin substitute in clinical settings.
In this study, VB-1 was reported to promote human hair follicle growth by enhancing Wnt/β-catenin signaling and increasing human dermal papilla cell proliferation in vitro.