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    Did you mean Hair Follicle Stem Cell Niche?
    Glossary Hair Follicle Stem Cell Niche

    specialized microenvironment regulating hair follicle stem cells

    The Hair Follicle Stem Cell Niche, also known as the HFSC Niche, is a specialized microenvironment within the hair follicle that houses and regulates hair follicle stem cells. This niche provides the necessary signals and support to maintain stem cell function, enabling the cyclical growth, rest, and shedding phases of hair. It plays a crucial role in hair regeneration and repair, making it a key area of interest in studies related to hair loss and regenerative medicine.

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    1. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin Aging Cell · 2009 · 62 citations
    2. Tumor suppressor identity can contribute to heterogeneity of phenotype in hair follicle stem cell‐induced squamous cell carcinoma Experimental Dermatology · 2016 · 8 citations
    3. 1349 Inducing fate changes at the hair follicle stem cell nice Journal of Investigative Dermatology · 2023
    4. Ox40-Cre–mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia JCI insight · 2022 · 1 citations
    5. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    6. Hair follicle-derived mesenchymal cells support undifferentiated growth of embryonic stem cells Experimental and Therapeutic Medicine · 2017 · 7 citations
    7. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations Journal of Clinical Investigation · 2011 · 178 citations
    8. Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss Cell Stem Cell · 2007 · 688 citations
    9. LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis Journal of Investigative Dermatology · 2024 · 1 citations
    10. Amelanocytic Anhidrotic Alopecia Areata-like Phenotype After Allogeneic Hematopoietic Cell Transplant Archives of Dermatology · 2012 · 5 citations
    11. Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype Frontiers in Genetics · 2022 · 37 citations
    12. Towards expansion of human hair follicle stem cells in vitro Cell Proliferation · 2011 · 14 citations
    13. State-dependent signaling by Ca<sub>v</sub>1.2 regulates hair follicle stem cell function Genes & development · 2013 · 27 citations
    14. Faculty Opinions recommendation of Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009
    15. A preliminary study of markers for human hair follicle melanin stem cell Chinese Medical Journal · 2019 · 1 citations
    16. LB1672 Senescent melanocytes in nevus skin stimulate hair growth Journal of Investigative Dermatology · 2023
    17. Keratinocyte Stem Cells: Role in Aging IntechOpen eBooks · 2022 · 1 citations
    18. Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells Nature · 2010 · 116 citations
    19. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009 · 330 citations
    20. The in vitro plasticity of hair follicle dermal and mesenchymal stem cells Durham e-Theses (Durham University) · 2008
    21. The role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function 2013 · 1 citations
    22. Microskin‐Inspired Injectable MSC‐Laden Hydrogels for Scarless Wound Healing with Hair Follicles Advanced Healthcare Materials · 2020 · 89 citations
    23. 1379 Cell of origin contributes to the melanoma diversity Journal of Investigative Dermatology · 2018
    24. The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells International Journal of Molecular Sciences · 2020 · 3 citations
    25. Regenerative potential of CD200- subpopulations of hair follicle bulge Frontiers in Cell and Developmental Biology · 2026
    26. Runx Family Genes in Tissue Stem Cell Dynamics Advances in Experimental Medicine and Biology · 2017 · 6 citations
    27. Niche work when you can get it: collagen XVII and the melanocyte stem cell Pigment Cell & Melanoma Research · 2011 · 2 citations
    28. Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation Cell Cycle · 2006 · 74 citations
    29. Isolation, Cultivation, and Morphological Characteristics of Hair Follicle Adult Stem Cells in the Bulge Region in Mouse and Human Microscopy research · 2020 · 1 citations
    30. The genetic evolution of skin squamous cell carcinoma: tumor suppressor identity matters Experimental Dermatology · 2016 · 6 citations