research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
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research LncRNA-miRNA-mRNA Regulatory Networks in Skin Aging and Therapeutic Potentials
ceRNA networks offer potential treatments for skin aging and wound healing.
research Molecular Mechanisms Affecting Development of Animal Fibers and Some Studies on Goats
The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.
research Single Molecule FISH for Hedgehog Signaling in Mouse Skin
Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
research Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology
The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.
research Therapeutic Potential of Stem Cells in Follicle Regeneration
Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
research Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
research Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
research Gene Expression Profile of Human Follicle Dermal Papilla Cells in Response to Camellia Japonica Phytoplacenta Extract
Camellia japonica extract may improve scalp health and promote hair growth.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Hair Follicles’ Transit-Amplifying Cells Govern Concurrent Dermal Adipocyte Production Through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Functional Mapping of the Mouse Hairless Gene Promoter Region
Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
research The Role of Wnt and Shh Signaling Systems in Noggin-Induced Tumorigenesis
Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.
research Stem Cell Plasticity Enables Hair Regeneration Following Lgr5+ Cell Loss
Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
research Bacteria Induce Skin Regeneration via IL-1β Signaling
Bacteria can help skin regenerate through a process called IL-1β signaling.
research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
Blocking a specific protein signal can make hair grow on mouse nipples.
research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
research Functional Redundancy of Frizzled 3 and Frizzled 6 in Planar Cell Polarity Control of Mouse Hair Follicles
Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
research Microneedling for Hair Loss
Microneedling is an effective and minimally invasive treatment for hair loss.
research Nevoid Basal Carcinoma Syndrome (Gorlin Syndrome) and Pronounced Androgenic Alopecia in a Woman with a Novel Mutation p.Leu1159fsx32 in the PTCH Gene
A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.
research Advances in Hair Restoration: Wnt/Beta-Catenin Pathway and Stem Cell-Based Therapies
New treatments for hair loss could involve using stem cells and a process called the Wnt/beta-catenin pathway to stimulate hair growth.
research Towards New Aspects of Melatonin Research in Dermato-Endocrinology
Melatonin protects skin and hair from damage and stress by acting as an antioxidant and influencing cell growth.
research In This Issue
Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
research Androgen Action and 3D Culture Conditions Influence Dermal Papilla Cells' Inductive Properties: The Role of Wnt Agonists/Antagonists Balance
DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
research Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Arctiin Blocks Hydrogen Peroxide-Induced Senescence and Cell Death Through MicroRNA Expression Changes in Human Dermal Papilla Cells
Arctiin helps protect hair cells from damage and death caused by oxidative stress.