research Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
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research Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor
LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia
PRP therapy and minoxidil combo works best for male hair loss.
research Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations
Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
research Th22 Is the Effector Cell of Thymosin β15-Induced Hair Regeneration in Mice
Th22 cells are essential for Tβ15-induced hair growth in mice.
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
research Wnt Signaling in Skin Organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research Accelerated Senescence in Skin in a Murine Model of Radiation-Induced Multi-Organ Injury
High-dose radiation speeds up aging in skin stem cells.
research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research Pannexin 3 Regulates Skin Development via Epiprofin
Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
research Expression Patterns of the Siah Genes in Postnatal Mouse Skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
research Catalytic-Dependent and -Independent Activities of Polycomb Repressive Complex 1 Differentially Regulate Skin Stem Cell Specification
PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
research Repairing the Lungs One Breath at a Time: How Dedicated or Facultative Are You?
Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Modulation of Genomic and Postgenomic Alterations in Non-Cancer Diseases and Critical Periods of Life
N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
research Effect of Marine-Derived Saccharides on Human Skin Fibroblasts and Dermal Papilla Cells
Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
research Protection Against Chemotherapy-Induced Alopecia
No treatment fully prevents hair loss from chemotherapy yet.
research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
research Stem Cell Secretome as a New Booster for Regenerative Medicine
Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
research 702 dsRNA Induces Ectopic KRT9 Expression via WNT/β-Catenin-Mediated Signaling
Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
research New Insights into the Role of Runx1 in Epithelial Stem Cell Biology and Pathology
Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
research Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
research Thymic Stromal Lymphopoietin Controls Hair Growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene helps improve wound healing in mice, especially in females.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Vitamin D and Calcium Signaling in Epidermal Stem Cells and Their Regeneration
Vitamin D and calcium are important for skin stem cell function and wound healing.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Progressive Expression of PPARGC1α Is Associated with Hair Miniaturization in Androgenetic Alopecia
Increased PPARGC1α relates to hair thinning in common baldness.