86 citations,
July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
57 citations,
November 1987 in “Pediatric Dermatology” Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.
53 citations,
November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
51 citations,
January 2004 in “Skin Pharmacology and Physiology” The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
46 citations,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
42 citations,
June 2009 in “Journal of Cosmetic Dermatology” Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.
35 citations,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
30 citations,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
24 citations,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
14 citations,
July 2015 in “Journal of Cosmetic Dermatology” Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
9 citations,
March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
9 citations,
November 2012 in “Archives of Dermatological Research” MC4R gene variants not linked to female hair loss.
8 citations,
October 1988 in “Clinics in Dermatology” Current research explores hair growth drugs, while future research aims for personalized treatments.
3 citations,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
1 citations,
February 2018 in “Madridge journal of dermatology & research” The plant extract remedy Satura® Rosta promotes hair growth and regrowth without negative effects.
July 2023 in “Biomolecules” The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
205 citations,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
92 citations,
November 2006 in “Proceedings of the National Academy of Sciences of the United States of America” BMP signaling controls hair follicle size and cell growth by affecting cell cycle genes.
March 2018 in “Nepal journal of dermatology, venereology & leprology” Hair loss linked to prostate enlargement; stress and family history important factors.
44 citations,
June 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
20 citations,
July 2008 in “Dermatologic Therapy” The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
5 citations,
February 2015 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” OCT can non-invasively diagnose follicular keratosis and other hair follicle disorders.
29 citations,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
99 citations,
June 2005 in “Journal of Cosmetic Dermatology” Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
8 citations,
July 2012 in “Cambridge University Press eBooks” Androgens can both increase body hair and cause scalp hair loss.
240 citations,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.