4 citations,
October 2016 Herbs like aloe vera and amla are effective and safe for treating hair loss.
3 citations,
November 2020 in “Biological Trace Element Research” Men with hair loss may lack zinc, copper, and vitamin D; supplements could help.
3 citations,
November 2014 in “Protein Expression and Purification” Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
1 citations,
March 2004 in “Journal of The European Academy of Dermatology and Venereology” Hair loss improved with treatment and successful transplant.
June 2022 in “Biomedical reports” STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
January 2015 in “Hair therapy & transplantation” New hair and scalp disease diagnosis methods are important for correct treatment.
March 1997 in “The American Journal of Cosmetic Surgery” A new hair transplant method showed promising results and a study found how deep a CO₂ laser can penetrate skin.
March 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Microneedling combined with platelet-rich plasma therapy is more effective for hair regrowth in androgenic alopecia than microneedling alone, but it's more painful.
434 citations,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
263 citations,
February 2011 in “Journal of Controlled Release” Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
199 citations,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
121 citations,
March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
106 citations,
September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
99 citations,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
98 citations,
June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” A cluster of sulfur-rich hair protein genes was found on chromosome 17.
89 citations,
November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
84 citations,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
82 citations,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
81 citations,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
74 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Minoxidil foam enters hair follicles and skin for hair growth.
68 citations,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
67 citations,
August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
60 citations,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
54 citations,
January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
43 citations,
July 2016 in “European journal of pharmaceutical sciences” Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
36 citations,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
34 citations,
July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
33 citations,
January 2021 in “Aesthetic Surgery Journal” Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
32 citations,
June 2017 in “Journal of Pharmaceutical Sciences” Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.