Hair Botox makes hair look healthier and fuller.
December 2025 in “Mendeley Data” This registered trial will investigate whether preoperative botulinum toxin can improve hair transplantation outcomes by enhancing blood flow and reducing ischemia in the scalp.
November 2025 in “Mendeley Data” This study outlines a randomized trial investigating the effects of botulinum toxin administered before hair transplantation to potentially improve outcomes by enhancing blood flow and reducing graft failure due to ischemia in androgenetic alopecia patients.
November 2011 in “Journal watch” Botox might help hair grow, but more research is needed.
September 2023 in “JPRAS Open” This review discusses botulinum toxin A as a treatment for various types of hair loss and reports no clinical results; the authors emphasize the need for comprehensive evaluations and further research.
This study found that in mice with alopecia areata, a single subcutaneous injection of botulinum neurotoxin serotype A significantly reduced hair loss and stimulated hair follicle regeneration.
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January 2022 in “Neurotoxicity Research” This study found that botulinum toxin type A injections in stressed mice appeared to normalize hair follicle regeneration cycles and reduced stress-related hair loss indicators.
December 2025 in “Mendeley Data” This article outlines a randomized trial to evaluate whether preoperative botulinum toxin administration can improve hair transplantation outcomes by reducing ischemia-induced graft failure.
November 2025 in “Journal of Microbiology and Biotechnology” In this study, combining Botulinum toxin type A with Platelet-rich plasma was found to enhance hair follicle growth and reconstruction, potentially through inflammation reduction and activation of the Wnt/β-catenin pathway via STMN1 protein modulation.
November 2025 in “Mendeley Data” This study outlines a randomized trial to assess if administering botulinum toxin before hair transplantation can improve outcomes by enhancing blood flow and reducing ischemia-induced graft failure in patients with androgenetic alopecia.
November 2025 in “Mendeley Data” This study explores the hypothesis that preoperative administration of botulinum toxin could enhance hair transplantation outcomes by improving scalp microenvironment and reducing ischemia-induced graft failure, using a randomized split-scalp controlled trial design.
September 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin is not effective or cost-efficient for treating male pattern baldness.
September 2023 in “Skin appendage disorders” This pilot study detailed the use of Hair-to-Hair-matching technology™ in a clinical trial to assess botulinum toxin's efficacy in treating male androgenetic alopecia, providing a precise method for evaluating hair count and thickness changes over time.
April 2024 in “Skin research and technology” This study suggests that while subcutaneous Botulinum Toxin Type A may offer short-term symptom improvement for female pattern hair loss, its effectiveness does not extend beyond three months.
This review discusses the use of botulinum toxin for hair and scalp disorders and reports mixed findings, with most studies showing mild or non-significant effects on hair growth.
September 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin is not effective for treating male hair loss.
June 2026 in “Dermatology and Therapy” In this retrospective analysis, patients with trichodynia who were unresponsive to standard treatments showed significant symptom improvement after receiving intradermal botulinum toxin type A, with nearly all patients benefiting, particularly those with scarring alopecia.
September 2001 in “PubMed”
August 2021 in “International Journal of Research in Dermatology” This article reviews various hair straightening methods, discussing their mechanisms and potential effects on hair, but it reports no new clinical results.
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October 2014 in “Plastic & Reconstructive Surgery Global Open” In this case study, Botulinum toxin type A injections were associated with improved hair growth and scalp condition in a patient with radiation-induced alopecia, though the mechanisms remain speculative.
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May 2021 in “European medical journal” This review reports that botulinum toxin is used in dermatology not only for treating rhytides but also for conditions like rosacea, hyperhidrosis, and menopause-related flushing, although its full safety and efficacy profile requires more research.
July 2005 in “CME: Your SA Journal of CPD” This review discusses the use of botulinum toxin as a treatment for chronic headache, highlighting its safety and acceptance among patients, but reports no new clinical results; the authors stress the need for comparative studies with standard treatments.
July 2020 in “Journal of The American Academy of Dermatology” This article discusses the authors’ response to comments on their study about intradermal botulinum toxin's effect on androgenetic alopecia, reporting no new findings.
This study found that subcutaneous administration of Botulinum toxin type A significantly reduced histamine-induced itch intensity and neurogenic inflammation in human skin compared to saline.
This study found that Botox® was most effective at a 25 U/ml concentration, while Dysport® and Neurobloc® were optimal at 100 U/ml for producing anhidrotic areas after injections.
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January 2017 in “Skin appendage disorders” This review discusses botulinum toxin's experimental off-label uses in dermatology, highlighting promising results but emphasizing the need for more clinical trials to confirm efficacy and safety.
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November 2010 in “Plastic and Reconstructive Surgery” This study suggests that Botox injections may increase hair count and reduce hair loss in men with androgenetic alopecia, potentially through increased blood flow and oxygen to the scalp.
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August 2014 in “Journal of Craniofacial Surgery” In this study on rats, botulinum toxin–A injection was reported to reduce contraction in wounds and skin grafts, with changes in inflammation and collagen arrangement also observed.
15 citations
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April 2020 in “Journal of The American Academy of Dermatology” In this study, intradermal injection of botulinum toxin was associated with increased hair growth in men with androgenetic alopecia through the suppression of TGF-β1 secretion from dermal papilla cells.
15 citations
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May 2013 in “Ophthalmic Plastic and Reconstructive Surgery” In this case study, repetitive botulinum type A toxin injections led to almost complete resolution of severe chronic pain in a patient with Parry-Romberg syndrome.