Botulinum Neurotoxin Type A Combined With Platelet-Rich Plasma Promotes Hair Follicle Growth And Regeneration Via STMN1 Modulation And Wnt/β-Catenin Pathway Activation

This study explores the combined effects of Botulinum Neurotoxin Type A and Platelet-Rich Plasma (PRP) on hair follicle growth and regeneration, demonstrating that this combination enhances hair growth by upregulating growth factors such as ALP, FGF, PDGF, VEGF, and versican, while increasing β-catenin and Ki-67 expression and reducing inflammatory biomarkers like IL-6 and TNF-α. The research concludes that the combination promotes hair follicle growth by activating the Wnt/β-catenin pathway through STMN1 modulation, suggesting a promising therapeutic approach for hair regeneration. The study does not specify the number of participants involved.