Response to Ong et al., 'Hair-Raising Costs: Evaluating Botulinum Toxin Treatment for Androgenetic Alopecia'

    André Luiz Vairo Donda, Rita Fernanda Cortez de Almeida, Daniel Fernandes Melo, Paulo Müller Ramos, Carla Jorge Machado, Sidney Frattini, Daniela Alves Pereira Antelo, Carlos Baptista Barcauí
    TLDR Botulinum toxin is not effective for treating male hair loss.
    The study discussed in the document evaluates the efficacy of botulinum toxin (BT) for treating male androgenetic alopecia (AGA) through a triple-blind, randomized clinical trial. Despite the potential of new treatment options, the study concludes that BT does not play a role in managing male AGA. The trial used a high dose of BT (50 IU/cm²) and precise methodologies, such as hair-to-hair trichoscopy, to ensure accurate results. The authors emphasize the importance of considering efficacy, safety, and cost-effectiveness in treatment decisions, highlighting that their findings may help prevent unnecessary societal costs from ineffective therapies.
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