Preoperative Botulinum Toxin Injection Does Not Improve Hair Transplantation Outcomes: A Split-Scalp Randomized Controlled Trial

    December 2025 in “ Mendeley Data ”
    Li Jiaqi
    TLDR Botulinum toxin injections do not improve hair transplant results.
    A recent split-scalp randomized controlled trial investigated the impact of preoperative botulinum toxin (BoNT) injections on hair transplantation outcomes. Despite BoNT's known benefits in enhancing scalp microenvironment through improved oxygenation and blood flow, the study found that preoperative BoNT administration did not improve hair transplantation outcomes. The trial aimed to address challenges such as graft survival and ischemia-induced graft failure, but the results indicate that BoNT does not enhance the success of hair transplants.
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