Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified a specific LIPH gene mutation (736T>A) as common in Japanese patients with autosomal recessive woolly hair/hypotrichosis, potentially indicating its role in the condition's manifestation within this population.

This article reviews how environmental pollutants like glyphosate, fluoride, and electromagnetic fields may contribute to mitochondrial dysfunction and adverse health effects such as cancer and chronic diseases, but reports no new research findings.

In this study, researchers found that hair follicle-derived mesenchymal stem cells, modified to overexpress extracellular matrix protein 1, significantly improved liver function and reduced liver damage in cirrhotic mice by inhibiting hepatic stellate cell activation and TGF-β/Smad signaling.

This study found that Brigatinib-loaded nanospanlastics demonstrated enhanced cytotoxicity against lung cancer cells and improved drug stability and release compared to free Brigatinib.

The book is a comprehensive and current guide on hair disorders, with minor flaws.

In this study, researchers identified two significant genetic polymorphisms in the 3'-UTR of the HSP70 gene in Moa buffalo, which may play an important role in heat adaptation, providing insights for conservation and performance improvement in tropical climates.

This article reports that while surgical excision is often the best treatment for SCC, intralesional cidofovir also showed success without systemic toxicity in the case discussed.

In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.

This review highlights the potential of targeting hepatic stellate cell ferroptosis as a treatment strategy for liver fibrosis, underscoring the need for further research into ferroptosis mechanisms in these cells to better understand and combat this condition.

In this study, researchers identified similar presence of various nicotinic and muscarinic AChRs in lesional and normal epidermis, suggesting that tobacco-delivered nicotine may exacerbate acne inversa by interacting with endogenously produced acetylcholine.

This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.

This study found that among pediatric patients with inborn errors of immunity, severe COVID-19 was linked to chronic lung disease, hypogammaglobulinemia, and musculoskeletal abnormalities, with chronic pulmonary illness being a major risk factor, while long-term effects included fatigue, hair loss, and red eye.

This guide reviews the biology of sebaceous glands and their evaluation methods, emphasizing their roles beyond lipid production in skin health and disease, and reports no new research results.

This study found that small extracellular vesicles derived from human adipose tissue could promote soft tissue regeneration and increase M2 macrophage polarization, suggesting a promising cell-free approach to tissue repair.

In this study, researchers in Baghdad observed that women with PCOS who tested positive for CagA-IgG, a marker for H. pylori infection, showed significantly elevated insulin resistance and fasting blood sugar levels, regardless of metformin treatment, compared to controls.

This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.

This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.

This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

This study proposes reclassifying PCOS into two distinct phenotypes based on androgen levels and suggests androgen supplementation may overcome IVF resistance in one group with advancing age.

This study found that transgenic mice overexpressing human H-ferritin showed mild growth retardation and a temporary hairless phenotype, highlighting H-ferritin's physiological roles.

This study found that electric shaving was the most effective and safest method for preoperative hair removal in mice, compared to depilatory cream and sodium sulfide, which negatively affected wound healing.

This proof-of-concept study reported that a new, ultra-fast, one-step immunohistochemistry method improved the interpretation of Mohs surgery slides, particularly for poorly differentiated tumors.

This review highlights that both human-derived and plant-derived exosomes show anti-inflammatory and antioxidant properties, with human exosomes being better for targeted medicinal treatments due to their ability to transport healing drugs, while plant exosomes are more scalable and cost-effective for cosmetic applications.

In this study, a new topical formulation containing amine-activated carboxymethyl chitosan and hydrolyzed extracellular matrix showed promising results in a mouse model by reducing oxidative stress, inflammation, and promoting hair regeneration, potentially offering an alternative treatment for inflammatory hair loss.

This study found that conditioned medium from human dental pulp stem cells (particularly under hypoxic conditions) improved keratinocyte survival and hair regrowth in a chemotherapy-induced alopecia mouse model and did not promote tumor growth, suggesting potential for safe therapeutic use.

This study found that histomorphological evaluation of nail punch biopsies is useful for diagnosing various nail-related dermatoses, with psoriasis being the most common condition observed.

This study suggests that specific structural features of minoxidil analogs, such as hydrophobic and hydrogen bond field contributions, are key to enhancing lysyl hydroxylase inhibitory activity, which could inform future hair growth treatments.

No link found between hair loss severity and PSA levels in men.