Comparative Analysis of Plant Exosomes and Human-Derived Exosomes: Structural Differences and Emerging Applications

February 2026 in “ International Journal of Recent Surgical and Medical Sciences ”

Lipi Singh, Ritesh Gupta, Sukhbir Singh, Priya Kiran

human-derived exosomes plant-derived exosomes H-EVs P-EVs anti-inflammatory antioxidant immunomodulatory skin growth hair growth

Studysummary This review highlights that both human-derived and plant-derived exosomes show anti-inflammatory and antioxidant properties, with human exosomes being better for targeted medicinal treatments due to their ability to transport healing drugs, while plant exosomes are more scalable and cost-effective for cosmetic applications.

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research Efficacy of Placental-Derived Mesenchymal Stem Cell Exosome Therapy in Treating Androgenetic Alopecia: A Clinical Trial Study

December 2024 in “Research Square (Research Square)”

In this phase I/II clinical trial, placenta-derived mesenchymal stem cell exosome therapy significantly improved hair density and diameter, and reduced hair loss in patients with androgenetic alopecia, though further large-scale studies are needed to confirm these results and investigate the underlying molecular mechanisms.

research Clinical Applications of Exosomes in Cosmetic Dermatology

February 2024 in “Skin health and disease”

This review reports that exosomes show potential in regenerative and cosmetic dermatology for applications like wound healing and hair loss mitigation, but their clinical use is currently limited by high costs, complex processing, and sparse clinical evidence.