10 citations,
July 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
2 citations,
May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
1 citations,
June 2021 in “Dermatological reviews” AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
1 citations,
October 2017 in “Journal of Investigative Dermatology” Hair care products reduced hair roughness, a combination of Stemoxydine and Resveratrol increased hair density, fermented mackerel oil promoted hair growth, and genes TERT and Bmi-1 helped create new hair follicles.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
October 2017 in “Journal of Investigative Dermatology” Mackerel fermented fish oil protects skin cells from damage by UVB light.
October 2017 in “Journal of Investigative Dermatology” The combination of Stemoxydine® and Resveratrol improves hair density in women with Female Pattern Hair Loss.
October 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
65 citations,
November 2013 in “International Clinical Psychopharmacology” Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.
43 citations,
February 2009 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
15 citations,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
277 citations,
February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
75 citations,
August 2008 in “PLOS ONE” Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.
22 citations,
July 2014 in “Hormones” Metformin may help treat neuroendocrine tumors.
8 citations,
September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
5 citations,
January 2018 in “Interdisciplinary sciences: computational life sciences” Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
April 2023 in “Journal of Investigative Dermatology” KY19382 helps to regrow hair and create new hair follicles.
321 citations,
December 2009 in “Journal of Dermatological Science” Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
81 citations,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
21 citations,
May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.
55 citations,
May 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
10 citations,
January 2020 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
308 citations,
September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
22 citations,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
2 citations,
September 2022 in “Annals of Oncology” Mirvetuximab soravtansine improves quality of life and reduces symptoms more than standard chemotherapy in ovarian cancer patients.
December 2016 in “Therapeutic Delivery” New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.
20 citations,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.