12 citations,
July 2020 in “Aging” The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.
12 citations,
August 2017 in “Archives of Pharmacal Research” Lecithin-based microparticles can deliver minoxidil for hair growth effectively with less skin irritation.
11 citations,
January 2014 in “Egyptian Journal of Dermatology and Venereology” Women losing hair might have lower levels of vitamin D.
10 citations,
November 2018 in “Genetics in medicine” Lack of cystatin M/E causes thin hair and dry skin.
10 citations,
November 2015 in “American Journal of Primatology” Monkeys with more anxious or inhibited temperaments tend to have less hair loss.
7 citations,
January 2020 in “Scientific Reports” Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.
7 citations,
July 2019 in “Clinics in Dermatology” Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
7 citations,
March 2018 in “Asian-Australasian journal of animal sciences” OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.
6 citations,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
5 citations,
February 2019 in “PloS one” Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
5 citations,
February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
4 citations,
September 2012 in “Journal of Nanoscience and Nanotechnology” Dermoscopy helps dermatologists diagnose different types of hair loss accurately without always needing a biopsy.
4 citations,
April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
3 citations,
January 2023 in “Nutrients” Hordenine may help hair grow by activating a specific cell growth pathway.
3 citations,
May 2022 in “Clinical endocrinology” Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.
3 citations,
January 2019 in “Dermatology and therapy” Scalp massages may help stabilize or regrow hair in people suffering from hair loss, regardless of age, gender, or use of other treatments.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
2 citations,
June 2022 in “Cells” 3D cell cultures are better for testing hair growth treatments than 2D cultures.
2 citations,
May 2022 in “Clinical, Cosmetic and Investigational Dermatology” Trichoscopy and pathological examination both have unique benefits and cannot completely replace each other in evaluating hair.
2 citations,
December 2021 in “Pharmaceutics” Finasteride-loaded proniosomes effectively promote hair growth in mice.
2 citations,
May 2020 in “Journal of visualized experiments” Controlled light treatment in mouse skin speeds up healing and hair growth.
2 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
2 citations,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
2 citations,
June 1980 in “International Journal of Dermatology” Scalp biopsies are important for diagnosing hair loss conditions.
1 citations,
November 2023 in “Biomedicines” Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
1 citations,
February 2023 in “Pharmaceutics” New UVA-responsive nanocapsules effectively kill microorganisms in hair follicles when activated by light.
1 citations,
October 2022 in “Journal of dermatological science” Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.
1 citations,
February 2022 in “Clinical, Cosmetic and Investigational Dermatology” TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.