96 citations
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October 1987 in “The Journal of Clinical Endocrinology & Metabolism” This study found that long-term GnRH agonist administration in premenopausal women with polycystic ovarian disease resulted in persistent suppression of ovarian steroid secretion, while adrenal steroid levels remained unchanged.
December 2024 in “Open Repository of the University of Porto (University of Porto)” This study consisted of a pharmacy master's thesis detailing practical experiences during a hospital and community pharmacy internship and scientific investigations into the off-label use of dutasteride for androgenetic alopecia and oral vaccines for urinary tract infection prophylaxis, emphasizing therapeutic applications and mechanisms of action.
August 2021 in “Clinical and Experimental Dermatology” This article discusses the introduction of the term 'prepubertal pattern hair loss' to describe hair thinning in children under 10 without physical abnormalities, and reports no new clinical findings.
April 2023 in “Journal of Investigative Dermatology” In this study using a mouse model of Pemphigus vulgaris, researchers found that loss of desmoglein 3 adhesion in hair follicle stem cells triggers a regenerative program restoring stem cell function, requiring Hedgehog pathway suppression.
April 2016 in “Journal of Investigative Dermatology” This study found that Pdgfα signaling is crucial for maintaining dermal adipose tissue in mice by initiating dermal adipocyte stem cell proliferation, with implications for age-related skin defects.
91 citations
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August 2015 in “Anais Brasileiros De Dermatologia” This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.
May 2022 in “Journal of Immunology” In this study, a TGF-β mimic molecule from Heligmosomoides polygyrus was observed to enhance wound healing in mice, with improved tissue regeneration and specific immune cell recruitment without increased scarring.
November 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced a novel scarless healing material called pgPE, made from a porous UHMWPE nanomembrane, and found that it promotes complete skin reconstruction and hair follicle regeneration by alleviating hypoxia and modulating immune responses to foster scar-free wound healing.
This study found that the Arabidopsis cation chloride cotransporter (CCC1) is crucial for regulating pH and processes in the trans-Golgi-network/early endosome, impacting plant growth and stress responses.
April 2019 in “Journal of Investigative Dermatology” The study suggests that variability in platelet-derived growth factors in PRP is influenced by both patient-to-patient differences and the devices used for PRP preparation, contributing to inconsistent clinical outcomes in hair loss treatments.
January 2008 in “xPharm: The Comprehensive Pharmacology Reference” 9 citations
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October 2017 in “Frontiers in plant science” This study found that the peach gene CTG134 mediates auxin-ethylene crosstalk, affecting root hair growth and hormone-regulated processes in plants.
2 citations
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January 2015 in “BioMed Research International” This article reviews various aspects of growth factor research, highlighting their role in treatments and emphasizing the need for further clinical trials to validate their efficacy in biomedical applications.
November 2014 in “Clinical Neurophysiology” High doses of progesterone can reduce seizures in mice.
September 2021 in “Physiology News” This abstract lacks specific study results and appears to contain a placeholder text or design template instead of research findings.
November 2024 in “Open Repository of the University of Porto (University of Porto)” This report details a six-month internship experience, split between hospital and community pharmacy settings, which enhanced practical skills and theoretical knowledge in pharmaceutical care and highlighted the pharmacist's role in ensuring safe medication use.
20 citations
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August 2015 in “International Journal of Molecular Medicine” This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.
January 2023 in “Methods in molecular biology” This article reviews methods for examining the localization and activity of ROP GTPase, cortical microtubule organization, and F-actin dynamics in plant cell models, but reports no new experimental results.
29 citations
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February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications” This study developed a fully automated HPLC method for accurately quantifying finasteride in human plasma, achieving a detection limit of 1 ng/ml with validated application in pharmacokinetic studies.
December 2022 in “International Journal of Research in Dermatology” This pilot study found that growth factor concentrate therapy improved hair growth in patients with androgenetic alopecia, was well tolerated, and achieved high patient satisfaction.
1 citations
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January 2005 in “Chinese Journal of Hospital Pharmacy” This study developed a stable and reliable HPLC-ESI-MS method for determining finasteride levels in human plasma, suitable for pharmacokinetic studies.
12 citations
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August 2001 in “PubMed” This study found that contrast enhanced phototrichogram (CE-PTG) significantly improved detection of various hair types and growth stages in androgenetic alopecia compared to standard PTG and was comparable to biopsy analysis.
January 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that the novel culture condition gHFEM, which includes Y-27632 and bFGF, optimally promotes the proliferation and pluripotency of goat hair follicle stem cells in vitro.
38 citations
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June 2018 in “Plant & cell physiology/Plant and cell physiology” This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.
March 2024 in “Frontiers in reproductive health” This study explored how an educational intervention on reducing phthalate exposure through hair care product choices influenced the hair care practices of pregnant women of color, identifying key life stages and themes related to these practices, including cultural influences, product impacts, and individual autonomy.
September 2023 in “Journal of the American Academy of Dermatology” This study evaluated the effect of guselkumab on moderate to severe plaque psoriasis and found that median PASI improvements increased from around 60% at week 4 to over 90% by week 12 of treatment across multiple clinical trials.
December 2024 in “The Eurasia Proceedings of Science Technology Engineering and Mathematics” This study found that levels of gamma-glutamyl cysteine synthetase (ꝩ-GCS) were significantly higher in PCOS patients, suggesting a key role of glutathione metabolism in the disease's progression.
April 2023 in “Journal of Investigative Dermatology” In this study, researchers developed a mouse model of scarring alopecia and observed significant reductions in CD200R expression in affected skin, potentially linking this signaling pathway to immune attacks on hair follicles and suggesting new treatment targets for scarring hair loss.
9 citations
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January 1999 in “Journal of Liquid Chromatography & Related Technologies” This article discusses using high performance liquid chromatography to optimize mobile phase composition for separating synthesis products of Finasteride, without reporting new clinical results.
7 citations
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April 2024 in “Skin Research and Technology” This study found that ChatGPT provided fairly accurate answers to common psoriasis-related questions, as rated by medical experts, although it doesn't fully replace professional medical judgment or diagnosis.