27 citations
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January 2018 in “Drug Delivery” In this study, researchers investigated a new local drug delivery system using glycol chitosan hydrogel and doxorubicin (GC10/DOX) for thyroid cancer in mice, finding it produced a stronger antitumor effect compared to conventional treatment methods.
21 citations
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March 2021 in “Molecules” This study found that a new quercetin-loaded self-nanoemulsifying drug delivery system improved quercetin bioavailability by 149.8% compared to its suspension in rats.
May 2023 in “International Journal of Trichology” In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.
3 citations
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January 1985 in “Drug development and industrial pharmacy” In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.
16 citations
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December 2016 in “Skin appendage disorders” This study analyzed patch test results to identify allergens causing scalp contact dermatitis, finding nickel, cobalt, and balsam of Peru among the most common in the patient population.
April 2026 in “Biomolecules” In this study, researchers synthesized biomedical polyurethanes incorporating curcumin and varying PEG content to enhance water solubility and control curcumin release, finding that higher PEG content improved hydrophilicity, swelling, and degradation, while maintaining excellent antioxidant and antibacterial activities, suggesting promise for biomedical applications.
30 citations
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December 2019 in “PLoS ONE” This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.
1 citations
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June 2021 in “International journal of pharmaceutical compounding” This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
November 2024 in “Polymers for Advanced Technologies” In this study, a hydrogel wound dressing infused with tannic acid demonstrated excellent antibacterial activity and promoted effective wound healing in rat burn models, leading to wound closure in 17 days and hair regrowth by day 21.
January 2016 in “Frontiers in Bioengineering and Biotechnology” This study developed keratin-based hydrogels with improved water solubility and tunable properties, demonstrating excellent cytocompatibility, suggesting potential for biomedical applications.
February 2024 in “PubMed” This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
2 citations
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May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.
November 2022 in “Asian Journal of Pharmaceutical Research” In this study, the researchers developed a cellulose-based hydrogel that provides sustained drug release with improved bioavailability and stability over time.
61 citations
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September 2016 in “NPG Asia Materials” This study developed thermo-reversible glycol chitosan hydrogels that effectively form and maintain 3D cell spheroids within one day, offering a simplified method for creating biologically realistic cultures for tissue regeneration and drug screening applications.
12 citations
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June 2023 in “International Journal of Molecular Sciences” This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
32 citations
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November 2020 in “Nanomaterials” This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.
28 citations
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November 2020 in “Fluid Phase Equilibria” In this study, researchers measured the solubility of Minoxidil in supercritical CO₂ under various temperature and pressure conditions and created models to estimate solubility based on different predictive approaches.
19 citations
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January 2020 in “Journal of Biophotonics” This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal mehendi gel formulated for natural hair coloring and scalp care, finding it safe for topical use and demonstrating benefits like natural coloring and scalp conditioning.
January 2024 in “Biomaterials Research” This study found that human hair follicle dermal papilla cells cultivated as 3D spheroids in hexanoyl glycol chitosan-coated dishes formed hair-like structures, with minoxidil enhancing growth, and successfully integrated into artificial skin models, suggesting advancements for hair loss treatments and skin restoration therapies.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
January 2024 in “Advances in health sciences research/Advances in Health Sciences Research” This study found that a hair tonic made from sweet potato leaf extract demonstrated strong antifungal activity against Malassezia furfur in vitro, comparable to 2% ketoconazole, suggesting its potential as an antidandruff treatment.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated a rosemary oil-based herbal hair serum with satisfactory physicochemical and microbiological characteristics, suggesting potential as a plant-based hair care option, but its long-term stability and efficacy need further investigation.
522 citations
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January 2001 in “Cancer investigation” This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
19 citations
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November 2017 in “Journal of Pharmaceutical Sciences” This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.
12 citations
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August 2017 in “Archives of Pharmacal Research” In this study, lecithin-based microparticle formulations of minoxidil showed enhanced skin penetration and comparable hair growth effectiveness to commercial products in mice, while minimizing skin irritation often seen with standard minoxidil solutions.
April 2020 in “Dermatology and therapy” In this study, the novel 5% minoxidil formulation significantly increased scalp hydration and decreased redness in Indian men with androgenetic alopecia compared to alcohol-based formulations.
223 citations
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October 2020 in “Microsystems & Nanoengineering” This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.