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Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

PCOS is a common and costly condition in North American women, causing various health issues like obesity, diabetes, and fertility problems.

Polycystic Ovary Syndrome (PCOS) is a common but often undiagnosed disorder in women that can cause irregular periods, infertility, and other symptoms, and can be managed with lifestyle changes, medication, and sometimes surgery.

Gene therapy in mice increased lifespan and improved health without causing cancer.

People need different amounts of biotin based on age and it's important for health, with many foods providing enough.

Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.

People need different amounts of biotin based on age, and not getting enough can cause health problems.

Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Higher testosterone levels in Nigerian women with PCOS are linked to glucose disorders like diabetes.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Teens with PCOS have a higher risk of type 2 diabetes and need regular glucose checks.

FDG PET/CT scans can change cancer treatment plans for dogs.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Polycystic Ovary Syndrome (PCOS) symptoms vary globally, with bloating, high cholesterol, and glucose levels being common; the current diagnostic criteria may need refining.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

About 19.4% of Iranian women in the study have Polycystic Ovary Syndrome, with the most common type involving irregular periods and high male hormone levels, but their heart and metabolic health is similar to women without the condition.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

High testosterone increases heart disease risk in women with PCOS.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.