February 2023 in “JEADV Clinical Practice” This case report describes a girl with uncombable hair syndrome who showed significant improvement in hair combability and growth rate after two cycles of oral biotin supplementation.
February 2024 in “Medicina-lithuania” This narrative review explores how obesity, related diseases, and bariatric surgery can impact hair health and the hair development cycle, highlighting potential effects such as hair thinning and telogen effluvium.
14 citations
,
April 2000 in “Animal Science/Animal science” This article explores how various nutrients and metabolic processes impact wool and hair follicle function in animals but reports no new experimental findings.
24 citations
,
July 1987 in “Dermatologic Clinics” This article reviews various causes of hair loss linked to systemic factors, noting that careful history and examination can lead to accurate diagnosis, but reports no new clinical results.
March 1993 in “Neuroscience letters” This summary outlines the essential roles and recommended daily intakes of biotin, while discussing consequences and mechanisms of deficiency, but presents no new research findings.
74 citations
,
July 1979 in “Lancet” This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.
2 citations
,
December 2014 This review discusses the role of biotin in metabolism and the consequences of its deficiency, reporting no new clinical results.
24 citations
,
May 2017 in “PubMed” This review evaluates biotin's popularity and its purported benefits for hair improvement but finds no clinical evidence supporting its efficacy.
1 citations
,
January 2010 in “Springer eBooks” Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
239 citations
,
July 2002 in “Clinical and Experimental Dermatology” This review explores the role of nutritional factors in hair loss, noting that iron and l-lysine supplementation may benefit some individuals, while excessive supplements can lead to hair shedding.
70 citations
,
June 2010 in “Clinics in Dermatology” This review discusses how changes in hair and skin may indicate underlying vitamin deficiencies and emphasizes the need to identify populations at risk for these deficiencies; it reports no new results.
August 2022 in “Nutrients” This ex vivo study found that hair follicles in female pattern hair loss exhibited nutrient insufficiency and dormant metabolism, but maintained nutrient uptake capability, suggesting potential benefits of nutritional supplementation as an adjunct therapy.
August 2023 in “Natural Resources for Human Health” This paper offers a detailed overview of B vitamins, detailing their importance for energy, cognition, and metabolism, conditions leading to their deficiencies, symptoms of deficiencies, and the foods rich in these essential nutrients.
6 citations
,
October 1980 in “Archives of Dermatology” This review discusses various metabolic and vitamin disorders affecting hair structure, including Menkes' syndrome, arginosuccinicaciduria, and recent findings on vitamin-related alopecia, but reports no new clinical results.
1 citations
,
January 1997 in “Proceedings of the British Society of Animal Science” This review addresses the role of biotin in animal metabolism, emphasizing the need for further research to understand its dietary and microbial sources in different developmental stages in pre-ruminant and mature ruminant animals, without reporting new experimental results.
October 2025 in “Jurnal Ilmiah Kedokteran dan Kesehatan” This literature review reports that multivitamin supplementation can enhance hair density and quality in people with suboptimal nutritional status but warns that excessive intake of certain vitamins and minerals may cause hair loss.
57 citations
,
February 2018 in “Journal of the American Academy of Dermatology” This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.
July 2026 in “IntechOpen eBooks” This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.
July 2018 in “International journal of clinical & experimental dermatology” This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.
65 citations
,
October 2018 in “Frontiers in cellular and infection microbiology” This study observed that dandruff in Indian women is associated with a distinct scalp microbiome, including specific bacterial and unknown Malassezia species, with implications for nutrient homeostasis and cell-host adhesion pathways.
7 citations
,
January 2010 in “Animal” This review discusses studies on hair growth and protein synthesis in hair follicles, highlighting the differing responses of mohair and cashmere goat follicles to signaling molecules, biotin, and amino acids, but contains no new results.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that a shampoo containing a 6-active ingredient complex increased β-Catenin production in human hair follicle dermal papilla cells to levels comparable to Finasteride, suggesting potential for promoting hair growth. It also showed good cleaning efficacy, volume, and shine in a sensorial study.
2 citations
,
October 2023 in “Biology” This review highlights cobalt's essential role in vitamin B12 metabolism and its biomedical applications but also warns of health risks from high levels and environmental contamination, discussing remediation methods like phytoremediation.
Nutrition plays a key role in managing skin disorders, with specific dietary changes helping improve conditions like acne, dermatitis, psoriasis, alopecia, and skin cancer.
50 citations
,
March 1992 in “PubMed” This review discusses the clinical manifestations of malnutrition in children, particularly highlighting the overlapping skin changes from various nutrient deficiencies, and reports no new clinical results.
26 citations
,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that cutaneous pyridoxal 5'-phosphate hydrolase activity may be carried out by an enzyme different from the classical tissue-nonspecific alkaline phosphatase in human and mouse skin.
January 2012 in “Vitamins & trace elements” This study observed that smokers and alcohol consumers with androgenetic alopecia had significantly lower serum levels of antioxidant vitamins, and these habits may trigger earlier onset of alopecia in susceptible individuals.
9 citations
,
November 2014 in “Journal of Cutaneous Medicine and Surgery” This study found that a majority of dermatologists in Saudi Arabia believe in using vitamins and minerals to treat hair loss but emphasized the need for more research to confirm their effectiveness.
5 citations
,
March 2021 in “International Journal of Dermatology” This study found that adding 10 mg/day of biotin to isotretinoin treatment for acne improved hair growth and maintained skin hydration, potentially reducing isotretinoin's mucocutaneous side effects.
134 citations
,
December 2018 in “Dermatology and Therapy” This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.