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Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Mild thyroid issues don't affect the metabolism and hormones of women with PCOS.

Skin tags in obese individuals may indicate higher cardiovascular risk.

Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.

Lavandula stoechas helps wounds heal faster in diabetic and non-diabetic rats.

Men with androgenetic alopecia may have a higher risk of metabolic syndrome.

Testosterone increases sexual behavior in female capuchin monkeys.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Higher Galectin-3 levels are linked to insulin resistance and may predict androgenetic alopecia severity.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

Women with PCOS often have sleep problems, including sleep apnea, which are linked to obesity and depression.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.