Protective Effect of DA-9401 on Acute Use of Finasteride on Sprague-Dawley Rats

    February 2018 in “ The Journal of Sexual Medicine ”
    Keshab Kumar Karna, Young Ho Shin, K. Soni, Byung Ihn Choi, Hyun-Chul Kim, Jong-Kyu Park
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    TLDR DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
    The document contains summaries of various studies conducted on Sprague-Dawley rats to investigate the protective effect of DA-9401 on acute use of finasteride. The studies found that DA-9401 had a protective effect on hair loss, liver and kidney function, blood glucose levels, and the negative effects of finasteride on the rats' prostate and seminal vesicles. DA-9401 was also found to improve hormonal imbalance and prevent endoplasmic reticulum stress in the testes. The studies suggest that DA-9401 may be a potential treatment for hair loss caused by finasteride and infertility caused by finasteride use.
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