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Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

A new gene variant causes glucocorticoid resistance in a mother and son.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Adrenal disorders can cause lasting brain and behavior issues in children.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Hair follicle stem cells help skin heal and grow during stretching.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Genomic approach finds new possible treatments for hair loss.

Curcumin may help reverse aging by targeting specific genes.

Testosterone is crucial for development, growth, and various body functions in mammals.

Excess androgens may cause PCOS, not just be a symptom.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.