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Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.

Stem-cell therapy shows promise for skin conditions but needs more research.

Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.

Improved understanding of stem cell mechanisms can enhance skin tissue engineering.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Sirtuin 1 could be a potential drug target for treating hypertrophic scars.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Dental pulp stem cells might not reliably become neurons.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.

Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.

Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

Stem cell niches support, regulate, and coordinate stem cell functions.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.