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Gene regulation could revolutionize hair color by altering pigmentation from within.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

FGF5 gene mutations cause long hair in domestic cats.

Germinated hemp seed extracts help prevent hair loss and promote hair growth.

Hemp seed biomaterials may reduce hair loss and improve hair growth.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Significant progress was made in understanding PXE, but effective treatments are still needed.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Finasteride blocks progesterone's effect on absence seizures in rats.

Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Androgens may block hair growth signals, targeting this could treat hair loss.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.