Hair Coloration by Gene Regulation: Fact or Fiction?

    November 2015 in “ Trends in biotechnology ”
    Teresa Matamá, Andreia C. Gomes, Artur Cavaco‐Paulo
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    TLDR Gene regulation could revolutionize hair color by altering pigmentation from within.
    The document explored the potential of using gene regulation to develop new hair coloring products that change hair color from the inside out. It focused on the role of melanin and genetic factors in hair pigmentation, and the use of nanocarriers for targeted delivery to hair follicles. The research suggested that understanding the molecular basis of hair greying could lead to effective antigreying cosmetics by activating melanocytes. It also discussed the use of small RNA oligonucleotides, such as siRNA, to regulate gene activity and alter hair color. The authors believed that advancements in understanding genetic mechanisms and delivery systems could revolutionize hair care by enabling genetic modulation of hair color.
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