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research Modulating the stem cell niche for tissue regeneration

480 citations , August 2014 in “Nature Biotechnology”

This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.

research QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities

April 2019 in “Molecular Informatics”

This study employed multiple linear regressions to analyze hydantoin analogues and produced a model with strong predictive abilities for designing new androgen receptor modulators.

research Racial variations in COVID‐19 deaths may be due to androgen receptor genetic variants associated with prostate cancer and androgenetic alopecia. Are anti‐androgens a potential treatment for COVID‐19?

71 citations , April 2020 in “Journal of Cosmetic Dermatology”

This article discusses the potential link between genetic variants associated with androgen receptor activity and racial variations in COVID-19 mortality, suggesting a possible role for anti-androgens in treatment, but reports no new clinical findings.

research Biotechnology in Hair Care (II): Growth Modulation

April 2016 in “CRC Press eBooks”

This chapter reviews the potential applications of genetic engineering in hair growth research and development but provides no new experimental results, emphasizing the need for innovative approaches in the field.

research Hair Coloration by Gene Regulation: Fact or Fiction?

15 citations , November 2015 in “Trends in biotechnology”

This article discusses strategies for changing hair color by regulating target genes in hair follicles using advanced delivery systems, but it reports no new experimental findings.

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community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community Stop Complaining about Creatine. You're just fixated on shedding.

73 upvotes 1 year ago

Creatine is unlikely to cause hair loss as it does not raise DHT levels. Hair loss is more likely due to genetics, medications, or lifestyle changes.

community Regular middle aged guy, taking 5mg minoxidil, 1.1mg finasteride and biotin combo pill. 3 months progress.

151 upvotes 1 year ago

A 45-year-old man experienced positive hair regrowth using a combination pill of 5mg minoxidil, 1.1mg finasteride, and 1mg biotin over three months. He reported minimal side effects and prefers this treatment over hair transplants.

community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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learn microbiota modulator

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