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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Improving skin barrier and using antifungal treatments can help manage dandruff.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

Older skin has higher cancer risk due to inflammation and stem cell issues.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

Hair follicles are valuable for regenerative medicine and wound healing.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Regulatory T cells are essential for normal and improved wound healing in mice.