research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
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research Tumor Necrosis Factor Alpha, Interferon Gamma, and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin
TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
research Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?
Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.
research An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata
Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
research Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata
JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research Cicatricial Alopecia: Early Diagnosis and Treatment Strategies
Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
research Interferon in the Treatment of Cutaneous T-Cell Lymphoma
Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.
research Hair Growth-Promoting Effects of Enz MoriL on Human Dermal Papilla Cells Through Modulation of the Wnt/β-Catenin and JAK-STAT Signaling Pathways
Enz_MoriL from mulberry leaves helps hair growth by affecting specific cell pathways.
research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice
Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
research LB789 Novel IFNγ Aptamer TAGX-0003 Protected Hair Follicles from Immune Privilege Collapse and Reversed Alopecia Areata-Like Phenotype in Humanized Mouse Model
TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
research Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors
JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
research Effects of Crataegi Fructus Water Extract on Hair Growth and Gene Expression in Dermal Papilla Cells
Crataegi Fructus water extract helps hair grow better and thicker.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Adipose and Hair Function: An Apparent Connection
Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
research Preclinical Evidence Supporting Selective Inhibition of Tyrosine Kinase 2-Dependent, IL-12-Mediated Signaling as a Novel Strategy for Alopecia Areata Management
Blocking TYK2 might be a new way to treat hair loss from alopecia areata.
research Folliculocentric Papules and Alopecia in a 70-Year-Old Woman Diagnosed with Graham-Little-Piccardi-Lassueur Syndrome
A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
research Lack of Efficacy of Apremilast in 9 Patients with Severe Alopecia Areata
Apremilast did not work for treating severe alopecia areata.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research Adipose Transcriptome in the Scalp of Androgenetic Alopecia
The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.
research Long Non-Coding RNA AL136131.3 Inhibits Hair Growth Through Mediating PPARγ in Androgenetic Alopecia
A specific RNA molecule blocks hair growth by affecting a protein related to hair loss conditions.
research More Expression of IL-17 Than IFN-γ from CD49a-Negative Tissue-Resident Memory T Cells at the Hair Bulge and Hair Bulb Region in the Scalp of Chronic Alopecia Areata Patients According to the Foxp3+ mTregs Depletion
IL-17 and certain immune cells are linked to more severe alopecia areata.
research Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles
Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.
research Cicatricial Alopecia Symposium 2011: Lipids, Inflammation, and Stem Cells
The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.
research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ
Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
research What Is Behind the 'Swarm of Bees' in Alopecia Areata
Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins
Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
research Intradermal Adipocytes Mediate Fibroblast Recruitment During Skin Wound Healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Case of Alopecia Induced by Sorafenib, Possible Mechanism Similar to Alopecia Areata
Sorafenib may cause hair loss in a way similar to alopecia areata.
research Mouse Models of Alopecia Areata: C3H/HeJ Mice Versus the Humanized AA Mouse Model
The humanized AA mouse model is better for testing new alopecia areata treatments.